Clinical resources for healthcare professionals on bleeding and clotting disorders in women and girls
Bleeding and clotting disorders in women and girls, including von Willebrand disease, heavy menstrual bleeding, venous thromboembolism and rare coagulation factor deficiencies, remain significantly underrecognized across specialties. Hematologists, gynecologists, obstetricians and primary care providers need access to current clinical guidelines, diagnostic tools and evidence-based treatment protocols to close that gap.
The ISTH has developed this centralized hub to make finding that information faster and easier. Here you will find curated peer-reviewed articles organized by topic, clinical guidance documents and resources from our collaborative partners working to advance care in women's thrombosis and hemostasis. Our goal is to support healthcare professionals with the evidence needed to improve diagnosis, treatment and quality of life for women at every stage of life.
Curated resources for healthcare professionals
Healthcare providers play a critical role in diagnosing and managing bleeding and clotting disorders in women and girls, from heavy menstrual bleeding and von Willebrand disease to pregnancy-associated thrombosis. This curated resource hub offers clinical tools, global guidelines and actionable steps organized around your needs. Select a category below to navigate to your resources.
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Support by topic:
Resources for healthcare professionals on women's bleeding and clotting
The following resources are curated by subject and developed in collaboration with ISTH and its collaborative partners to support healthcare professionals, researchers and anyone working to improve care for women and girls with bleeding and clotting disorders. Resources include peer-reviewed articles, research papers, clinical guidelines and expert guidance. The ISTH Global Public Affairs Committee has vetted all resources to ensure accuracy, relevance and scientific integrity.
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Select a topic below to explore resources in that area. If you are a collaborative partner with resources you would like added to this collection, share them with us.
ACOG Committee Opinion: Screening and management of bleeding disorders in adolescents with heavy menstrual bleeding
American College of Obstetricians and Gynecologists
An official committee opinion from the ACOG with recommendations for screening and managing bleeding disorders in adolescents with heavy menstrual bleeding.
Venous thromboembolism in women with breast and gynaecological cancers: What do we know and what should we do?
Clinical and Applied Thrombosis/Hemostasis
A peer-reviewed article from Clinical and Applied Thrombosis/Hemostasis examining the current evidence and clinical recommendations for managing venous thromboembolism risk in women with breast and gynecological cancers.
CAT Guidelines: 2022 International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19
ISTH
The 2022 international clinical practice guidelines provide evidence-based recommendations for the treatment and prevention of cancer-associated thrombosis, including considerations for patients with COVID-19.
Estrogen, progestin, and beyond: thrombotic risk and contraceptive choices
American Society of Hematology
An American Society of Hematology resource examining the thrombotic risks associated with estrogen and progestin-based contraceptives and guidance for supporting informed contraceptive decision-making in women with bleeding and clotting disorders.
Combined oral contraceptives and the risk of thrombosis
International Journal of Molecular Sciences
A peer-reviewed article from the International Journal of Molecular Sciences reviewing the mechanisms and evidence behind venous thromboembolism risk associated with combined oral contraceptive use in women.
Hormonal therapies and venous thrombosis: Considerations for prevention and management
Research and Practice in Thrombosis and Haemostasis
A clinical review published in Research and Practice in Thrombosis and Haemostasis outlining key considerations for preventing and managing venous thrombosis risk in women using hormonal therapies.
ISTH clinical guidance and guidelines for women's health
The ISTH produces evidence-based clinical practice guidelines and guidance documents that provide practical recommendations for managing thrombosis and hemostasis disorders across the reproductive lifespan.
Developed by multidisciplinary expert panels, these resources address clinically important topics in women's health and offer informed guidance where randomized controlled trial data may be limited.
Alongside its guidelines, the ISTH offers validated clinical tools to support real-world decision-making, including VTE risk assessment protocols, the ISTH Bleeding Assessment Tool (BAT) and the Pictorial Blood Assessment Chart (PBAC). Browse the full collection of women's health guidelines, guidance documents and clinical tools.
Global support:
Collaborative networks
Navigating women's health challenges in thrombosis and hemostasis often requires collaboration beyond your immediate practice.
The ISTH has curated a comprehensive network of global and regional societies, organizations and associations dedicated to advancing care in this specialized field.
Whether you're seeking expert consultation on complex cases, looking to expand your knowledge through professional development opportunities or connecting with colleagues who share your focus on women's health, these organizations provide the specialized expertise and community support essential to delivering optimal patient care.
Explore ISTH resources
The ISTH provides comprehensive educational resources and research publications to advance clinical practice in thrombosis and hemostasis.
Access curated women's health content, continuing education through the ISTH Academy, and peer-reviewed research from our flagship journals.
The ISTH Academy delivers continuing medical education through webinars, courses and expert content in thrombosis and hemostasis. Educational resources support healthcare professionals advancing clinical knowledge in bleeding and clotting disorders.
The Journal of Thrombosis and Haemostasis (JTH) publishes peer-reviewed research advancing diagnosis and treatment of bleeding and clotting. Original research, clinical investigations and guidelines shape global practice in thrombosis and hemostasis.
Research and Practice in Thrombosis and Haemostasis (RPTH) is an open-access journal publishing peer-reviewed advances in bleeding and clotting. Global researchers and clinicians access the latest evidence-based research in thrombosis and hemostasis care.
Clinical resources from our collaborative partners
Finding reliable clinical information on women's bleeding and clotting disorders just got easier. The ISTH has partnered with leading organizations in thrombosis and hemostasis to bring healthcare professionals a curated collection of evidence-based resources on conditions including von Willebrand disease, venous thromboembolism, heavy menstrual bleeding and thrombophilia, all in one place. Explore the resources below to support accurate diagnosis, informed treatment decisions and better patient outcomes.
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