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Clinical resources for healthcare professionals on bleeding and clotting disorders in women and girls

Bleeding and clotting disorders in women and girls, including von Willebrand disease, heavy menstrual bleeding, venous thromboembolism and rare coagulation factor deficiencies, remain significantly underrecognized across specialties. Hematologists, gynecologists, obstetricians and primary care providers need access to current clinical guidelines, diagnostic tools and evidence-based treatment protocols to close that gap.
 
The ISTH has developed this centralized hub to make finding that information faster and easier. Here you will find curated peer-reviewed articles organized by topic, clinical guidance documents and resources from our collaborative partners working to advance care in women's thrombosis and hemostasis. Our goal is to support healthcare professionals with the evidence needed to improve diagnosis, treatment and quality of life for women at every stage of life.

Female doctor and patient discussing bleeding risks

Curated resources for healthcare professionals

Healthcare providers play a critical role in diagnosing and managing bleeding and clotting disorders in women and girls, from heavy menstrual bleeding and von Willebrand disease to pregnancy-associated thrombosis. This curated resource hub offers clinical tools, global guidelines and actionable steps organized around your needs. Select a category below to navigate to your resources.

Support by topic:
Resources for healthcare professionals on women's bleeding and clotting 

The following resources are curated by subject and developed in collaboration with ISTH and its collaborative partners to support healthcare professionals, researchers and anyone working to improve care for women and girls  with bleeding and clotting disorders. Resources include peer-reviewed articles, research papers, clinical guidelines and expert guidance. The ISTH Global Public Affairs Committee has vetted all resources to ensure accuracy, relevance and scientific integrity.

Select a topic below to explore resources in that area. If you are a collaborative partner with resources you would like added to this collection, share them with us.

Simple guide to haemophilia testing in women and girls

Haemophilia Foundation Australia

Accessible patient-facing guide covering genetic and factor level testing for haemophilia in females, including infographics, personal stories and answers to common questions.

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Bleeding disorders and abnormal bleeding toolkit

Haemophilia Foundation Australia

Practical resource helping women with bleeding disorders navigate disclosure conversations with family, partners, employers and healthcare providers, including guidance on privacy rights.

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Bleeding disorders and abnormal bleeding teaching toolkit

Let's Talk Period

A patient and provider education toolkit from Let's Talk Period designed to support conversations about bleeding disorders and abnormal uterine bleeding in clinical and community settings.

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Let's Talk Girls Affected by Hemophilia

Let's Talk Period

Patient-centered infographic on heavy menstrual bleeding in girls affected by hemophilia.

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Women with bleeding disorders

Haemophilia Foundation Australia

Hub page covering bleeding disorders in women and girls, including haemophilia, von Willebrand disease, genetic testing, symptoms, treatment and the HFA Female Factors project.

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Bleeding disorders in neonates

Haemophilia Foundation Australia

Accessible patient-facing guide covering genetic and factor level testing for haemophilia in females, including infographics, personal stories and answers to common questions.

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Factsheet on HRT for women who have a risk or history of blood clots.

The Menopause Chairty

Factsheet on HRT for women who have a risk or history of blood clots.

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Thrombosis Canada clinial guidelines

Thrombosis Canada

A Thrombosis Canada hub of evidence-based clinical guides supporting healthcare providers in the assessment and management of thrombotic conditions across a range of clinical settings.

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Clinical guidelines: Pediatric thrombosis

Thrombosis Canada

A Thrombosis Canada clinical guide for healthcare providers on the assessment and management of thrombosis in pediatric patients.

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Clinical guidelines: Pediatric thrombosis

Thrombosis Canada

A Thrombosis Canada clinical guide for healthcare providers on the assessment and management of thrombosis in pediatric patients.

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Management of heavy menstrual bleeding for patients on anticoagulation

Thrombosis Canada

A Thrombosis Canada clinical guide for healthcare providers on evaluating and managing heavy menstrual bleeding in patients receiving anticoagulation therapy, including assessment tools, hormonal and non-hormonal treatment options and follow-up recommendations.

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Management of heavy menstrual bleeding for patients on anticoagulation

Thrombosis Canada

A Thrombosis Canada clinical guide for healthcare providers on evaluating and managing heavy menstrual bleeding in patients receiving anticoagulation therapy, including assessment tools, hormonal and non-hormonal treatment options and follow-up recommendations.

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ISTH clinical guidance and guidelines for women's health

The ISTH produces evidence-based clinical practice guidelines and guidance documents that provide practical recommendations for managing thrombosis and hemostasis disorders across the reproductive lifespan.

 

Developed by multidisciplinary expert panels, these resources address clinically important topics in women's health and offer informed guidance where randomized controlled trial data may be limited.

 

Alongside its guidelines, the ISTH offers validated clinical tools to support real-world decision-making, including VTE risk assessment protocols, the ISTH Bleeding Assessment Tool (BAT) and the Pictorial Blood Assessment Chart (PBAC). Browse the full collection of women's health guidelines, guidance documents and clinical tools.

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Global support:
Collaborative networks

Navigating women's health challenges in thrombosis and hemostasis often requires collaboration beyond your immediate practice.

 

The ISTH has curated a comprehensive network of global and regional societies, organizations and associations dedicated to advancing care in this specialized field.

 

Whether you're seeking expert consultation on complex cases, looking to expand your knowledge through professional development opportunities or connecting with colleagues who share your focus on women's health, these organizations provide the specialized expertise and community support essential to delivering optimal patient care.

Meet our partners
Doctors doing hematology rounds

Explore ISTH resources

The ISTH provides comprehensive educational resources and research publications to advance clinical practice in thrombosis and hemostasis.

 

Access curated women's health content, continuing education through the ISTH Academy, and peer-reviewed research from our flagship journals.

The ISTH Academy delivers continuing medical education through webinars, courses and expert content in thrombosis and hemostasis.

The ISTH Academy delivers continuing medical education through webinars, courses and expert content in thrombosis and hemostasis. Educational resources support healthcare professionals advancing clinical knowledge in bleeding and clotting disorders.

The Journal of Thrombosis and Haemostasis publishes peer-reviewed research advancing diagnosis and treatment of bleeding and clotting.

The Journal of Thrombosis and Haemostasis (JTH)  publishes peer-reviewed research advancing diagnosis and treatment of bleeding and clotting. Original research, clinical investigations and guidelines shape global practice in thrombosis and hemostasis.

Research and Practice in Thrombosis and Haemostasis (RPTH) is an open-access journal publishing peer-reviewed advances in bleeding and clotting.

Research and Practice in Thrombosis and Haemostasis (RPTH) is an open-access journal publishing peer-reviewed advances in bleeding and clotting. Global researchers and clinicians access the latest evidence-based research in thrombosis and hemostasis care.

Clinical resources from our collaborative partners

Finding reliable clinical information on women's bleeding and clotting disorders just got easier. The ISTH has partnered with leading organizations in thrombosis and hemostasis to bring healthcare professionals a curated collection of evidence-based resources on conditions including von Willebrand disease, venous thromboembolism, heavy menstrual bleeding and thrombophilia, all in one place. Explore the resources below to support accurate diagnosis, informed treatment decisions and better patient outcomes.

Foundation for Women and Girls with Blood Disorders logo

Guidelines, screening tools and evidence

Visit FWGBD
Foundation for Women and Girls with Blood Disorders logo

Foundation for Women & Girls with Blood Disorders resource directory

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International Federation of Gynecology and Obstetrics (FIGO) logo

Resources from FIGO

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